37 research outputs found

    Design Space Exploration for Partially Reconfigurable Architectures in Real-Time Systems

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    International audienceIn this paper, we introduce FoRTReSS (Flow for Reconfigurable archiTectures in Real-time SystemS), a methodology for the generation of partially reconfigurable architectures with real-time constraints, enabling Design Space Exploration (DSE) at the early stages of the development. FoRTReSS can be completely integrated into existing partial reconfiguration flows to generate physical constraints describing the architecture in terms of reconfigurable regions that are used to floorplan the design, with key metrics such as partially reconfigurable area, real-time or external fragmentation. The flow is based upon our SystemC simulator for real-time systems that helps develop and validate scheduling algorithms with respect to application timing constraints and partial reconfiguration physical behaviour. We tested our approach with a video stream encryption/decryption application together with Error Correcting Code and showed that partial reconfiguration may lead to an area improvement up to 38% on some resources without compromising application performance, in a very small amount of time: less than 30 s

    Animalhumanité

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    Centré sur les représentations de l’expérimentation animale depuis le xvie siècle, aussi bien dans la science que dans la littérature, ce volume aborde les débats sur la vivisection et la cause animale dans leurs dimensions éthiques, philosophiques, culturelles voire idéologiques, en tenant compte de la perspective historique, de l’évolution de la conception des rapports entre l’homme et les animaux à partir du xixe siècle

    Multi-configurations et etat de charge du centre DX dans l'alliage AlxGaA1-xAs dope Si

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    SIGLEAvailable from INIST (FR), Document Supply Service, under shelf-number : T 83866 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

    Méthodologie de conception d'architectures reconfigurables dynamiquement pour des applications temps-réel

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    La reconfiguration dynamique des FPGA, malgré des caractéristiques intéressantes, peine à s installer dans l industrie principalement pour deux raisons. Tout d abord, les performances du contrôleur natif développé par Xilinx sont faibles et pourront résulter en un rapport entre le temps de reconfiguration et la période de la tâche trop importante pour une implémentation dynamique. Ensuite, le développement d une application reconfigurable dynamiquement demande un effort plus conséquent, notamment concernant l ordonnancement des tâches. Il est en effet impossible d évaluer une architecture et/ou un algorithme d ordonnancement pour vérifier si l application respectera bien ses contraintes de temps avant la phase d implémentation. Cette thèse s inscrit dans ce contexte et propose des solutions aux problématiques énoncées précédemment. Dans un premier temps, nous présenterons FaRM, un contrôleur de reconfiguration dynamique capable d atteindre les limites théoriques de la technologie grâce à un algorithme de compression efficient et une architecture optimisée. Ensuite, nous présenterons RecoSim, un simulateur d architectures reconfigurables en SystemC modélisant à un haut niveau d abstraction un tel système. Basé sur un modèle de coût du temps de reconfiguration avec FaRM, RecoSim permet notamment le développement et l évaluation d algorithmes d ordonnancement, qui sont des éléments clés des architectures temps-réel. Finalement, nous montrerons comment ces premières contributions sont utilisées au sein de FoRTReSS, un flot d exploration d architectures intégré avec les outils de développement Xilinx. Ces travaux ont été effectués dans le cadre du projet ANR ARDMAHN.Despite promising capabilities, FPGAs partial reconfiguration feature is not anchored in the industry yet, mostly for two reasons. First of all, Xiling controller shows low performance and might introduce a large time overhead compared to the task period, incompatible with the use of partial reconfiguration. Also, developing such a dynamic application requires an extra design effort compared to a static solution for developing scheduling strategies. Indeed, it is impossible to evaluate architecture and/or a scheduling algorithm to verify that real-time constraints are met before the implementation step. This thesis offers solutions to the issues previously mentioned. We will first introduce FaRM, a Fast Reconfiguration Manager reaching partial reconfiguration theoretical limits thanks to an efficient compression algorithm and an optimized architecture. Then, we present RecoSim, a high-level SystemC simulator for reconfigurable architectures. It makes use of FaRM reconfiguration overhead cost model to allow for developing and verifying SystemS compliant with Xilinx partial reconfiguration design flow. This work was carried out in the framework of project ARDMAHN, sponsored by the French National Research Agency.NICE-BU Sciences (060882101) / SudocSudocFranceF

    Low Power 28 nm Fully Depleted Silicon on Insulator 2.45 GHz Phase Locked Loop

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    International audienc

    Nitrogen and carbohydrate reserves in the grapevine (Vitis vinifera L. 'Chasselas'): the influence of the leaf to fruit ratio

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    Seasonal patterns of total organic nitrogen (N) and total non-structural carbohydrate (TNC) concentrations in relation to the leaf-fruit ratio (source-sink) were measured over three years at different grapevine phenological stages in one- and two-year-old canes, trunks and roots of the cultivar 'Chasselas' (Vitis vinifera L.). The highest N and TNC concentrations were observed during the period from dormancy until budbreak. A decrease in the N and TNC reserves was measured in the different organs (canes, trunks and roots) from budbreak, reaching minimum values around flowering, except for the N concentration in the roots, which was lowest during the period between bunch closure and veraison. N storage was highest in the roots and occurred from veraison until leaf fall. The N concentration in the trunks and canes represented approximately half of that measured in the roots. TNCs accumulated preferentially in the roots and also in the trunks and canes during the growing season. The leaf area per vine (or canopy height) and yield both influenced the N concentration in the roots. High yield and low leaf area per vine decreased the N concentration in the roots. The leaf-fruit ratio, expressed as the "light-exposed leaf area per kg fruit", substantially influenced the N and TNC concentrations in the roots at harvest. The highest N and TNC concentrations in the roots were obtained when the leaf-fruit ratio approached 2.0 m2 of light-exposed leaf area per kg fruit

    Human Umbilical Cord Blood Endothelial Progenitor Cell-Derived Extracellular Vesicles Control Important Endothelial Cell Functions

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    Circulating endothelial progenitor cells (EPCs) play a pivotal role in the repair of diseases in which angiogenesis is required. Although they are a potentially valuable cell therapy tool, their clinical use remains limited due to suboptimal storage conditions and, especially, long-term immune rejection. EPC-derived extracellular vesicles (EPC-EVs) may be an alternative to EPCs given their key role in cell–cell communication and expression of the same parental markers. Here, we investigated the regenerative effects of umbilical cord blood (CB) EPC-EVs on CB-EPCs in vitro. After amplification, EPCs were cultured in a medium containing an EVs-depleted serum (EV-free medium). Then, EVs were isolated from the conditioned medium with tangential flow filtration (TFF). The regenerative effects of EVs on cells were investigated by analyzing cell migration, wound healing, and tube formation. We also analyzed their effects on endothelial cell inflammation and Nitric Oxide (NO) production. We showed that adding different doses of EPC-EVs on EPCs does not alter the basal expression of the endothelial cell markers nor change their proliferative potential and NO production level. Furthermore, we demonstrated that EPC-EVs, when used at a higher dose than the physiological dose, create a mild inflammatory condition that activates EPCs and boosts their regenerative features. Our results reveal for the first time that EPC-EVs, when used at a high dose, enhance EPC regenerative functions without altering their endothelial identity

    Reversible ventricular arrythmia induced by dasatinib

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    Ventricular arrhythmias induced by dasatinib are rare events, but physicians in charge of chronic myeloid leukemia patients should be aware of such potential complications and the need for regular ECG controls during treatment with tyrosine kinase inhibitors
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